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This is Peptide Nutrition 101 Clean Eatz Glutathione Depletion and Carbon Ion Radiation Potentiate Clustered DNA Lesions, Cell Death and Prevent Chromosomal Changes in Cancer Cells Progeny PLOS One Glow Peptide Protocol GHK Cu, BPC 157, TB 500 Neurogan Health The hype around a new class of injectable drugs is in overdrive, but they have yet to be properly tested. Read the full story from Kishor Napier Raman at the link in bio., Photo: Oscar Colman can injecting ghk cu cause cancer A Dermatologist's Take on the Copper Peptide (GHK Cu) Trend be Development of Cagrilintide, a Long Acting Amylin Analogue Journal of Medicinal Chemistry
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4.2 ★★★★★
Based on 11 reviews
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Product Reviews
★★★★★ 3
Slight difference
I’ve noticed a slight difference it’s only been a week so I’m going to keep using it. And I’ll be back with an update.
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Reviewed in the United States on April 27, 2026
★★★★★ 5
Bags NO more
I have tried many many many depuffing creams, gels, masks..etc… THIS WORKS.. day one I thought just a fluke… then i started using morning and at bed.. I am waking up with almost ZERO bags.. I haven’t looked this awake in the longest time.. I will continue to purchase this product!
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Reviewed in the United States on May 14, 2026
★★★★★ 5
Impressive after first use! Cooling and hydrating!
Update: I used too much product and it will pill. I knew I shouldn’t reapply more, but something in this serum is soothing and cooling to my under eye skin.
Immediately feels cooling and hydrating around my eyes - feels so good! This soothing feeling lingers for several minutes. I am suffering with allergies at this time and the cool metal tip is soothing and the shape contours well to my eye area. I am applying this under my eyes and to the eyelid area. The formula absorbs quickly. The pics I am including are from the first use and then approximately 10 minutes after application. The difference is SUBTLE, but this is ONE use and only 10 minutes later and I can already see that there is a change, likely temporary. Within this short amount of time, some of the puffiness has subsided and a few fine lines are diminished. I was just outside weed whacking and I’m a mess. I’m certain this will perform even better when used after washing my face and as a part of my skincare routine.
I plan to use in the am and pm until the I finish the tube. What I am expecting according to Paula’s Choice information is for my fine lines to diminish and for my eyelids to be less saggy after 4 weeks of consistent use. I hope to have a follow up review with excellent results - fingers crossed - you can see my tired and puffy eyes need all the help they can get!
The packaging design makes application easy due to the slender tube that is easy to hold while applying the peptide eye serum with the ergonomic, cooling metal tip. The cap has an insert to keep the product from drying out which is another positive aspect to the packaging.
The formula has Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7 & Tridecapeptide-1, Lysine Polypeptides, and Pseudoalteromonas Ferment Extract. It’s worth your time to do some quick research on the benefits of these ingredients to understand what they do. I don’t want to write a novel here in a review.
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Reviewed in the United States on April 22, 2026
★★★★★ 5
Excellent 30 minute depuff. Cruelty free science-backed formula. Skip the applicator gimmick.
I’ve been using this eye cream for two weeks, and the results are impressive for morning maintenance. Within 30 minutes of application, I can see the "just woke up" puffiness settle down and the skin start to tighten. It absorbs quickly and leaves a slight shine so you know exactly where you’ve applied it, but it dries down without any tacky or restrictive feeling.
While I'd never heard of Paula (Paula Begoun - "cosmetic cop") before, or whatever she was choosing, I am well versed in the world of eye serum. As someone with chronic allergies and a genetic predisposition for dark circles I'm always on the lookout for a treatment that works.
After researching I found that Paula’s Choice is well-known for their "Smart, Safe, Effective" philosophy, and this serum reflects that. It’s formulated with a heavy-hitting mix of peptides and antioxidants that focus on skin repair. Crucially for me, the brand is Leaping Bunny certified cruelty-free and entirely fragrance-free, which is a must for the sensitive skin around the eyes. While the brand isn’t 100% vegan (some products use animal by-products like beeswax), this product IS, is and they are transparent about their sourcing. This particular serum feels incredibly "clean" and non-irritating.
The metal applicator is well-contoured for the under-eye area and feels great initially, though it does have a learning curve. It warms up quickly against the skin, and it can be hard to judge how much pressure to use when it’s pressed against your face. I’ve found the best method is to squeeze the serum onto the applicator before touching it to your skin to ensure you get the right amount. Honestly, squeezing a pea sized amount onto your finger and skipping the applicator all together may be the play.
I know no cream is a "cure-all." However, for managing daily puffiness and noticeably firming the skin, this is an excellent serum that delivers on its promises without the "fluff" of unnecessary perfumes or harsh additives.
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Reviewed in the United States on April 25, 2026
★★★★★ 5
Cooling applicator feels great and the serum layers well under makeup
I’ve tried quite a few eye creams and serums over the years, and this one definitely feels more premium than most. The lightweight gel-serum texture absorbs quickly and doesn’t leave my under-eye area greasy or sticky, which is important because I usually apply concealer shortly after my skincare routine. It sits nicely under makeup and I haven’t noticed any pilling as long as I use a small amount.
The cooling metal applicator is honestly one of my favorite parts of this product. I keep it in the fridge sometimes and it feels especially nice in the morning when my eyes look tired or puffy. The applicator glides smoothly around the eye area and helps depuff a bit even before the serum fully absorbs. After a couple of weeks of consistent use, I’ve noticed my under-eye area looks a little more hydrated and smoother, especially with fine lines that tend to look worse when my skin is dry. I wouldn’t call the results dramatic, but my eyes do look more refreshed overall. The fragrance-free formula is also a big plus since a lot of eye products irritate my skin or make my eyes water.
The only downside for me is the price. The product works well and feels high quality, but $39 for a half ounce is definitely on the expensive side. Thankfully you only need a tiny amount each use, so the tube should last a while. Overall, I think it’s a solid eye serum if you’re looking for hydration, mild firming, and a soothing cooling application experience.
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Reviewed in the United States on May 6, 2026